Gong, Q., Wang, Y., He, L., Huang, F., Zhang, D., Wang, Y., Wei, X., Han, M., Deng, H., Luo, L., Cui, F., Hong, Yiguo and Liu, Y. (2023) Molecular basis of methyl-salicylate-mediated plant airborne defence. Nature, 622. pp. 139-148. ISSN Print: 0028-0836 Online: 1476-4687
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Abstract
Aphids transmit viruses and are destructive crop pests1. Plants that have been attacked by aphids release volatile compounds to elicit airborne defence (AD) in neighbouring plants2,3,4,5. However, the mechanism underlying AD is unclear. Here we reveal that methyl-salicylate (MeSA), salicylic acid-binding protein-2 (SABP2), the transcription factor NAC2 and salicylic acid-carboxylmethyltransferase-1 (SAMT1) form a signalling circuit to mediate AD against aphids and viruses. Airborne MeSA is perceived and converted into salicylic acid by SABP2 in neighbouring plants. Salicylic acid then causes a signal transduction cascade to activate the NAC2–SAMT1 module for MeSA biosynthesis to induce plant anti-aphid immunity and reduce virus transmission. To counteract this, some aphid-transmitted viruses encode helicase-containing proteins to suppress AD by interacting with NAC2 to subcellularly relocalize and destabilize NAC2. As a consequence, plants become less repellent to aphids, and more suitable for aphid survival, infestation and viral transmission. Our findings uncover the mechanistic basis of AD and an aphid–virus co-evolutionary mutualism, demonstrating AD as a potential bioinspired strategy to control aphids and viruses.
Item Type: | Article |
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Divisions: | College of Health, Life and Environmental Sciences > School of Science and the Environment |
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Copyright Info: | © 2024 Springer Nature Limited, Use of the AM is subject to an embargo period and our AM terms of use, which permit users to view, print, copy, download and text and data-mine the content, for the purposes of academic research, subject always to the full conditions of use., Under no circumstances may the AM be shared or distributed under a Creative Commons, or other form of open access license, nor may it be reformatted or enhanced. |
Depositing User: | Yiguo Hong |
Date Deposited: | 16 Feb 2024 15:17 |
Last Modified: | 05 Apr 2024 14:44 |
URI: | https://eprints.worc.ac.uk/id/eprint/13614 |
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