Rapid Interrogation of the Physical and Chemical Characteristics of Salbutamol Sulphate Aerosol from a Pressurised Metered-dose Inhaler (pMDI)

Tong, H-J.; Fitzgerald, C.; Gallimore, P.J.; Kalberer, M.; Kuimova, M.K.; Seville, Peter C.; Ward, A.D.; Pope, F.D.

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Tong, H-J., Fitzgerald, C., Gallimore, P.J., Kalberer, M., Kuimova, M.K., Seville, Peter C. ORCID: https://orcid.org/0000-0001-8546-3474, Ward, A.D. and Pope, F.D. (2014) Rapid Interrogation of the Physical and Chemical Characteristics of Salbutamol Sulphate Aerosol from a Pressurised Metered-dose Inhaler (pMDI). Chemical Communications, 50. pp. 15499-15502. ISSN Print: 1359-7345 Online: 1364-548X

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Output Type:

Article

Abstract:

Individual micron-sized solid particles from a Salamol® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung.

Additional Information:

The full-text of the published version cannot be supplied. Please check availability with your local library or Interlibrary Requests service.

The full-text of accepted version can be accessed via http://clok.uclan.ac.uk/13613/

Legacy Divisions (Admin Only):

College of Health, Life and Environmental Sciences > School of Science and the Environment

Academic Schools:

School of Science and the environment

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Depositing User:

Peter Seville

Date Deposited:

18 Feb 2019 12:20