University of Worcester Worcester Research and Publications
 
  USER PANEL:
  ABOUT THE COLLECTION:
  CONTACT DETAILS:

Sleep Loss as a Trigger of Mood Episodes in Bipolar Disorder: Individual Differences Based on Diagnostic Subtype and Gender

Swaden Lewis, K., Gordon-Smith, Katherine ORCID: https://orcid.org/0000-0003-4083-1143, Forty, L., Di Florio, A., Craddock, N., Jones, Lisa ORCID: https://orcid.org/0000-0002-5122-8334 and Jones, I. (2017) Sleep Loss as a Trigger of Mood Episodes in Bipolar Disorder: Individual Differences Based on Diagnostic Subtype and Gender. British Journal of Psychiatry, 211 (3). pp. 169-174. ISSN 0007-1250 Online:1472-1465

[img] Text
Accepted Sleep loss as a trigger of mood episodes in bipolar disorder individual differences based on diagnostic subtype and gender..docx - Accepted Version
Restricted to Repository staff only

Download (320kB) | Request a copy
[img]
Preview
Text
Accepted Sleep loss as a trigger of mood episodes in bipolar disorder individual differences based on diagnostic subtype and gender. (1).pdf - Accepted Version

Download (409kB) | Preview

Abstract

Background: Sleep loss may trigger mood episodes in people with bipolar disorder (BD) but individual differences could influence vulnerability to this trigger.

Aims: To determine whether bipolar subtype (BD-I or BD-II) and gender were associated with vulnerability to the sleep loss trigger.

Method: During a semi-structured interview, 3140 individuals (68% female) with BD (66% BD-I) reported whether sleep loss had triggered episodes of high or low mood. DSM-IV diagnosis of bipolar subtype was derived from case note and interview data.

Results: Sleep loss triggering episodes of high mood was associated with female gender (OR = 1.43, 95% CI 1.17-1.75, P <.001) and BD-I subtype (OR = 2.81, 95% CI 2.26-3.50, P <.001). Analyses on sleep loss triggering low mood were not significant following adjustment for confounders.

Conclusions: Gender and bipolar subtype may increase vulnerability to high mood following sleep deprivation. This should be considered in situations where patients encounter sleep disruption, such as shift-work and international travel.

Item Type: Article
Additional Information:

The full-text can be accessed via the Official URL.

Uncontrolled Discrete Keywords: sleep loss, bipolar disorder, diagnostic subtype, gender
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: College of Health, Life and Environmental Sciences > School of Allied Health and Community
Related URLs:
Depositing User: Katherine Gordon-Smith
Date Deposited: 19 May 2017 07:23
Last Modified: 09 Jul 2020 11:06
URI: https://eprints.worc.ac.uk/id/eprint/5515

Actions (login required)

View Item View Item
 
     
Worcester Research and Publications is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.