University of Worcester Worcester Research and Publications

Adverse Childhood Life Events and Postpartum Psychosis in Bipolar Disorder

Perry, Amy ORCID:, Gordon-Smith, Katherine ORCID:, Di Florio, A., Forty, L., Craddock, N., Jones, Lisa ORCID: and Jones, I. (2016) Adverse Childhood Life Events and Postpartum Psychosis in Bipolar Disorder. Journal of Affective Disorders, 205. pp. 69-72. ISSN Online: 0165-0327

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Women with bipolar disorder are at increased risk of postpartum psychosis. Adverse childhood life events have been associated with depression in the postpartum period, but have been little studied in relation to postpartum psychosis. In this study we investigated whether adverse childhood life events are associated with postpartum psychosis in a large sample of women with bipolar I disorder.

Participants were 432 parous women with DSM-IV bipolar I disorder recruited into the Bipolar Disorder Research Network ( Diagnoses and lifetime psychopathology, including perinatal episodes, were obtained via a semi-structured interview (Schedules for Clinical Assessment in Neuropsychiatry; Wing et al., 1990) and case-notes. Adverse childhood life events were assessed via self-report and case-notes, and compared between women with postpartum psychosis (n=208) and those without a lifetime history of perinatal mood episodes (n=224).

There was no significant difference in the rate of any adverse childhood life event, including childhood sexual abuse, or in the total number of adverse childhood life events between women who experienced postpartum psychosis and those without a lifetime history of perinatal mood episodes, even after controlling for demographic and clinical differences between the groups.

Adverse childhood life events were assessed in adulthood and therefore may be subject to recall errors.

We found no evidence for an association between adverse childhood life events and the occurrence of postpartum psychosis. Our data suggest that, unlike postpartum depression, childhood adversity does not play a significant role in the triggering of postpartum psychosis in women with bipolar disorder.

Item Type: Article
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Uncontrolled Discrete Keywords: postpartum psychosis, bipolar disorder, childhood adversity, adverse childhood life events, risk factors
Subjects: R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: College of Health, Life and Environmental Sciences > School of Allied Health and Community
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Depositing User: Amy Perry
Date Deposited: 14 Jul 2016 15:24
Last Modified: 14 Jul 2020 12:32

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