University of Worcester Worcester Research and Publications
 
  USER PANEL:
  ABOUT THE COLLECTION:
  CONTACT DETAILS:

Synthesis of Silver Nanoparticles Using Curcumin-Cyclodextrins Loaded into Bacterial Cellulose-Based Hydrogels for Wound Dressing Applications.

Gupta, A. ORCID: https://orcid.org/0000-0001-7901-1818, Briffa, S.M., Swingler, S., Gibson, H., Kannappan, V., Adamus, G., Kowalczuk, M. ORCID: https://orcid.org/0000-0002-2877-7466, Martin, Claire ORCID: https://orcid.org/0000-0002-5497-4594 and Radecka, I. ORCID: https://orcid.org/0000-0003-3257-8803 (2020) Synthesis of Silver Nanoparticles Using Curcumin-Cyclodextrins Loaded into Bacterial Cellulose-Based Hydrogels for Wound Dressing Applications. Biomacromolecules. ISSN 1526-4602 (In Press)

[img] Text
9130-AAM-with-cover-synthesis-of-silver-nanoparticles-using-curcumin-cyclodextrins-loaded-into-bacterial-cellulose-based-hydrogels-for-wound-dressing-applications.pdf - Accepted Version
Restricted to Repository staff only until 22 January 2021.

Download (2MB) | Request a copy

Abstract

Chronic wounds are often recalcitrant to treatment because of high microbial bioburden and the problem of microbial resistance. Silver is a broad-spectrum natural antimicrobial agent with wide applications extending to proprietary wound dressings. Recently, silver nanoparticles have attracted attention in wound management. In the current study, the green synthesis of nanoparticles was accomplished using a natural reducing agent, curcumin, which is a natural polyphenolic compound that is well-known as a wound-healing agent. The hydrophobicity of curcumin was overcome by its microencapsulation in cyclodextrins. This study demonstrates the production, characterization of silver nanoparticles using aqueous curcumin:hydroxypropyl-β-cyclodextrin complex and loading them into bacterial cellulose hydrogel with moist wound-healing properties. These silver nanoparticle-loaded bacterial cellulose hydrogels were characterized for wound-management applications. In addition to high cytocompatibility, these novel dressings exhibited antimicrobial activity against three common wound-infecting pathogenic microbes , , and .

Item Type: Article
Additional Information:

The full-text cannot be supplied for this item. Please check availability with your local library or Interlibrary Requests Service.

Uncontrolled Keywords: antimicrobial agents, metal nanoparticles, bacteria, nanoparticles hydrogels
Subjects: Q Science > QR Microbiology
R Medicine > R Medicine (General)
Divisions: College of Health, Life and Environmental Sciences > School of Science and the Environment
Related URLs:
SWORD Depositor: Prof. Pub Router
Depositing User: Claire Martin
Date Deposited: 06 Feb 2020 15:40
Last Modified: 03 Apr 2020 11:06
URI: https://eprints.worc.ac.uk/id/eprint/9130

Actions (login required)

View Item View Item
 
     
Worcester Research and Publications is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.