University of Worcester Worcester Research and Publications

Reporting from outside the lab: attending the ASH conference

Hillier, James (2019) Reporting from outside the lab: attending the ASH conference. The Biochemist, 41 (3). pp. 56-57. ISSN Print: 0954-982X, Online: 1740-1194

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Postgraduate, Early Career, Full and Emeritus Members of the Biochemical Society can apply for a General Travel Grant. These grants support attendance at scientific meetings, training courses, lab visits or any other event relevant to your career and encourage lifelong learning. James Hillier is currently investigating the role of the aminotransferase BCAT1 in acute myeloid leukaemia (AML) development. BCAT1 contains a CXXC motif, a feature of many antioxidant enzymes such as thioredoxin that are able to metabolize reactive oxygen species (ROS). His research focuses how altered expression of BCAT1 affects redox homeostasis and how this impacts processes dysregulated in cancer such as proliferation, differentiation and apoptosis. Cancer cells are known to favour pro-oxidative states that induce proliferative signalling yet maintain ROS at sub-lethal levels, therefore targeting the antioxidant capacity of BCAT1 to induce cell death, which may open a promising treatment option for patients with aberrant BCAT1 expression.

Item Type: Article
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The full-text of the online published article can be accessed via the official URL.

James Hillier is a final year PhD student within the Worcester Biomedical Research Group at the University of Worcester. He attended the American Society of Hematology (ASH) Annual Meeting (1–4 December 2018), held in San Diego, California, following the award of a travel grant from the Biochemical Society.

Uncontrolled Discrete Keywords: ASH conference, biochemical society, travel grant
Divisions: College of Health, Life and Environmental Sciences > School of Science and the Environment
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Depositing User: Karen Veitch
Date Deposited: 08 Nov 2019 09:51
Last Modified: 17 Jun 2020 17:33

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