University of Worcester Worcester Research and Publications

Prevalence of Cardiometabolic Risk Factors in First Episode Psychosis Patients

Smith, Jo, Griffiths, Lisa and Horne, Dominic (2016) Prevalence of Cardiometabolic Risk Factors in First Episode Psychosis Patients. In: 'Looking Back, Moving Forward' The 10th International Conference on Early Intervention in Mental Health, 19th - 22nd October 2016, Milan, Italy. (Unpublished)

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INTRODUCTION Previous research in patients with schizophrenia have shown a high prevalence of metabolic syndrome and disease progression (~30-40%) which presents an increased risk for cardiovascular disease and long-term mortality (Correll et al. 2014; Mitchell et al. 2013). To date, little is known about the prevalence of existing cardiometabolic risk factors at time of diagnosis. This study presents a clinical overview of the cardiometabolic risk profile in young people presenting with early psychosis from a UK early intervention in psychosis service. METHODS: Participants (n=45; age 24.4 ± 4.5 yrs, 71% male, 88.9% White British) clinically diagnosed with a first episode psychosis with <3 months (n=39) or< 6 months (n=6) Duration of Untreated Psychosis (DUP) were assessed for anthropometric, lifestyle behaviours and clinical measurements including resting heart rate, blood pressure, blood lipids, HbA1c, and prolactin. The majority (n=38, 84.4%) were in receipt of antipsychotic medication (8.9% Aripiprazole, 28.9% Olanzepine, 31.1% Quetiapine, 4.4% Risperidone, 2.2% Paliperidone, 6.7% Clozapine). Seven participants (15.6%) were not on any antipsychotic medication. RESULTS Table 1 presents the cardiometabolic risk status and self reported lifestyle behaviours at baseline by sex of this first episode psychosis patient sample (n=45). • Participants had high prevalence of cardiometabolic risk factors due to elevated values for BMI (38.1%), abdominal adiposity (57.5%), high blood pressure (30.8% prehypertensive; 20.5% hypertensive), elevated resting heart rate (44.7%), hypercholesterolemia (27.9%), suboptimal HDL levels (25.6%), and hypertriglyceridemia (42.1%). • Participants also self-reported poor lifestyle habits including: smoking (55.8%), alcohol use (37.2%), substance use (16.3%), poor diet (53.5%), and a sedentary lifestyle (39.5%). CONCLUSION • Young people with psychosis are at increased risk for cardiometabolic disorders due to elevated clinical markers and unhealthy lifestyle behaviours. • Physical health interventions are needed early in the treatment process to address the increased risk for cardiometabolic disorders in individuals recently diagnosed

Item Type: Conference or Workshop Item (Poster)
Additional Information:

A copy of the Poster Abstract for this title can be found at

Uncontrolled Keywords: SHAPE programme, SHINE, psychosis, schizophrenia, mental health, lifestyle behaviours, prevalence of metabolic syndrome and disease progression
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Q Science > QP Physiology
Divisions: Academic Departments > Institute of Health and Society
Academic Departments > Institute of Sport and Exercise Science
Related URLs:
Depositing User: Lisa Griffiths
Date Deposited: 20 Feb 2017 09:51
Last Modified: 13 Mar 2017 12:16

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