University of Worcester Worcester Research and Publications
 
  USER PANEL:
  ABOUT THE COLLECTION:
  CONTACT DETAILS:

White Adipose Tissue Re-growth after Partial Lipectomy in High Fat Diet Induced Obese Wistar Rats

Bueno, Allain and Habitante, C.A. and Oyama, L.M. and Estadella, D. and Ribeiro, E.B. and Oller do Nascimento, C.M. (2011) White Adipose Tissue Re-growth after Partial Lipectomy in High Fat Diet Induced Obese Wistar Rats. The Journal of Physiological Sciences, 61 (1). pp. 55-63. ISSN Print 1880-6546 Online 1880-6562

[img] Text
White adipose tissue re-growth after partial lipectomy.pdf - Published Version
Restricted to Repository staff only

Download (364kB) | Request a copy

Abstract

The effects of partial removal of epididymal (EPI) and retroperitoneal (RET) adipose tissues (partial lipectomy) on the triacylglycerol deposition of high fat diet induced obese rats were analyzed, aiming to challenge the hypothesized body fat regulatory system. Male 28-day-old wistar rats received a diet enriched with peanuts, milk chocolate and sweet biscuits during the experimental period. At the 90th day of life, rats were submitted to either lipectomy (L) or sham surgery. After 7 or 30 days, RET, EPI, liver, brown adipose tissue (BAT), blood and carcass were obtained and analyzed. Seven days following surgery, liver lipogenesis rate and EPI relative weight were increased in L. After 30 days, L, RET and EPI presented increased lipogenesis, lipolysis and percentage of small area adipocytes. L rats also presented increased liver malic enzyme activity, BAT lipogenesis, and triacylglycerol and corticosterone serum levels. The partial removal of visceral fat pads affected the metabolism of high fat diet obese rats, which leads to excised tissue re-growth and possibly compensatory growth of non-excised depots at a later time.

Item Type: Article
Additional Information:

The full-text cannot be supplied for this item. Please check availability with your local library or Interlibrary Requests Service.

Uncontrolled Keywords: partial lipectomy, high fat diet, obesity, Adipose tissue, Triacylglycerol deposition
Subjects: Q Science > Q Science (General)
Q Science > QP Physiology
Divisions: Academic Departments > Institute of Science and the Environment
Related URLs:
Depositing User: Tanya Buchanan
Date Deposited: 04 Aug 2016 09:23
Last Modified: 04 Aug 2016 09:23
URI: https://eprints.worc.ac.uk/id/eprint/4730

Actions (login required)

View Item View Item
 
     
Worcester Research and Publications is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.