Tör, M and Gordon, P and Cuzick, A and Eulgem, T and Sinapidou, E and Mert-Türk, F and Can, C and Dangl, J.L. (2002) Arabidopsis SGT1b Is Required for Defense Signaling Conferred by Several Downy mildew Resistance Genes. Plant Cell, 14 (5). pp. 993-1003. ISSN Print: 1040-4651 Online: 1532-298X
Full text not available from this repository.
Official URL: http://www.plantcell.org/cgi/content/full/14/5/993
We describe the identification of a mutant in the Arabidopsis accession Columbia (Col-0) that exhibits enhanced downy mildew (edm1) susceptibility to several Peronospora parasitica isolates, including the RPP7-diagnostic isolate Hiks1. The mutation was mapped to chromosome IV and characterized physically as a 35-kb deletion spanning seven genes. One of these genes complemented the mutant to full wild-type resistance against all of the Peronospora isolates tested. This gene (AtSGT1b) encodes a predicted protein of 39.8 kD and is an Arabidopsis ortholog of yeast SGT1, which was described originally as a key regulatory protein in centromere function and ubiquitin-mediated proteolysis. AtSGT1b contains three tetratricopeptide repeats at the N terminus followed by a bipartite chord-containing SGT domain and an SGT-specific domain at the C terminus. We discuss the role of AtSGT1b in disease resistance and its possible involvement in ubiquitin-mediated proteolysis in plants.
This is an Open Access article. The full-text can be accessed via the Official URL.
|Uncontrolled Keywords:||Arabidopsis, defence signaling, downy mildew genes|
|Subjects:||Q Science > QK Botany|
Q Science > QH Natural history > QH426 Genetics
Q Science > QH Natural history > QH301 Biology
Q Science > QR Microbiology
|Divisions:||Academic Departments > Institute of Science and the Environment|
Research Centres > National Pollen and Aerobiology Research Unit
|Deposited By:||Janet Davidson|
|Deposited On:||19 Jan 2011 19:53|
|Last Modified:||19 Jan 2011 19:53|
Repository Staff Only: item control page