University of Worcester Worcester Research and Publications
 
  USER PANEL:
  ABOUT THE COLLECTION:
  CONTACT DETAILS:

Symptom profile of postpartum and non-postpartum manic episodes in bipolar I disorder: a within-subjects study

Gordon-Smith, Katherine ORCID: https://orcid.org/0000-0003-4083-1143, Perry, Amy ORCID: https://orcid.org/0000-0002-9381-6636, Di Florio, A., Forty, L., Fraser, C., Casanova Dias, M., Warne, N., MacDonald, T., Craddock, N. and Jones, Lisa ORCID: https://orcid.org/0000-0002-5122-8334 (2020) Symptom profile of postpartum and non-postpartum manic episodes in bipolar I disorder: a within-subjects study. Psychiatry Research, 284. Article no. 112748. ISSN Online: 0165-1781 (In Press)

[img] Text
9141-Gordon-Smith-Perry-Jones-Postpartum and non-postpartum main text file 13 12 2019 FINAL ACCEPTED (1)_merged.pdf - Accepted Version
Restricted to Repository staff only until 2 January 2021.

Download (347kB) | Request a copy

Abstract

The relationship of postpartum mania to episodes of mania occurring outside the perinatal period among women with bipolar disorder remains controversial. Previous studies have used between-subjects designs to compare the clinical presentations of these episodes meaning the differences, in part, may reflect between-group differences. To overcome this we have undertaken within-subject comparisons of the symptom profile of postpartum and non-postpartum manic episodes in 50 women with DSM-IV bipolar I disorder. For each woman detailed symptom information on a postpartum episode of mania and a comparison non-postpartum manic episode was collected. The occurrence of manic, psychotic and depressive symptoms in these episodes were compared. Postpartum manic episodes had a significantly higher incidence of perplexity and excessive self-reproach. Classic manic symptoms, specifically pressured speech and increased sociability, were significantly less frequent in postpartum manic episodes. Overall there were significantly fewer manic symptoms and significantly more depressive symptoms in the postpartum episodes than in the non-postpartum episodes. The mixed presentation of postpartum manic episodes suggests childbirth may act as a pathoplastic trigger in women with bipolar disorder. The differences in symptom profiles suggests further research is warranted into whether differences in treatment response exist among women experiencing postpartum and non-postpartum manic episodes.

Item Type: Article
Additional Information:

Staff and students at the University of Worcester can access the full-text of the online published article via the official URL. External users should check availability with their local library or Interlibrary Requests Service.

Uncontrolled Keywords: bipolar disorder, postpartum mania, symptomatology
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: College of Health, Life and Environmental Sciences > School of Allied Health and Community
Related URLs:
Depositing User: Katherine Gordon-Smith
Date Deposited: 07 Feb 2020 12:56
Last Modified: 07 Feb 2020 12:56
URI: https://eprints.worc.ac.uk/id/eprint/9141

Actions (login required)

View Item View Item
 
     
Worcester Research and Publications is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.