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Rapid Interrogation of the Physical and Chemical Characteristics of Salbutamol Sulphate Aerosol from a Pressurised Metered-dose Inhaler (pMDI)

Tong, H-J., Fitzgerald, C., Gallimore, P.J., Kalberer, M., Kuimova, M.K., Seville, Peter C. ORCID: https://orcid.org/0000-0001-8546-3474, Ward, A.D. and Pope, F.D. (2014) Rapid Interrogation of the Physical and Chemical Characteristics of Salbutamol Sulphate Aerosol from a Pressurised Metered-dose Inhaler (pMDI). Chemical Communications, 50. pp. 15499-15502. ISSN Print: 1359-7345 Online: 1364-548X

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Abstract

Individual micron-sized solid particles from a Salamol® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung.

Item Type: Article
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The full-text of accepted version can be accessed via http://clok.uclan.ac.uk/13613/

Divisions: Divisions (2019 and before) > Academic Departments > Institute of Science and the Environment
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Depositing User: Peter Seville
Date Deposited: 18 Feb 2019 12:20
Last Modified: 24 Sep 2019 07:39
URI: https://eprints.worc.ac.uk/id/eprint/7558

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