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Epilepsy and Bipolar Disorder

Knott, Sarah and Forty, L. and Craddock, N. and Thomas, R.H. (2015) Epilepsy and Bipolar Disorder. Epilepsy & Behavior, 52 (Pt A). pp. 267-274. ISSN Print: 1525-5050 Online: 1525-5069

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Abstract

It is well recognized that mood disorders and epilepsy commonly co-occur. Despite this, our knowledge regarding the relationship between epilepsy and bipolar disorder is limited. Several shared features between the two disorders, such as their episodic nature and potential to run a chronic course, and the efficacy of some antiepileptic medications in the prophylaxis of both disorders, are often cited as evidence of possible shared underlying pathophysiology. The present paper aims to review the bidirectional associations between epilepsy and bipolar disorder, with a focus on epidemiological links, evidence for shared etiology, and the impact of these disorders on both the individual and wider society. Better recognition and understanding of these two complex disorders, along with an integrated clinical approach, are crucial for improved evaluation and management of comorbid epilepsy and mood disorders.

Item Type: Article
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Uncontrolled Keywords: Bipolar disorder, genetics, epilepsy, comorbidity
Subjects: R Medicine > R Medicine (General)
Divisions: Academic Departments > Institute of Health and Society
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Depositing User: Sarah Knott
Date Deposited: 04 Feb 2016 11:50
Last Modified: 04 Feb 2016 11:50
URI: https://eprints.worc.ac.uk/id/eprint/4126

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